![]() ![]() The huge variety of wounds and the wide range of dressings available make it difficult to choose the right wound treatment. New dressings made of genetically modified flax are a chance to increase the effectiveness of treatment of difficult healing wounds. Conclusions: All the obtained flax fibers in the form of flax dressings did not lose their wound-healing properties under the influence of the technological process. Necrosis is not statistically significant. At the same time, the greatest increase was observed with the use of B14 fabric. After 48 h of incubation of HEMVEC, NHEK and THP-1 cells with the tested fabrics, the growth of S-phase cells was noticed in all cases. The smallest cells in the apoptotic phase were in cultures treated with M50 fiber on an area of 0.5 cm. The tested fabrics caused a statistically significant decrease in the total protein content in skin cancer (except for 0.5 cm of Nike-type fabrics). Results: All tested linen fabrics did not raise the number of necrotic cells. Moreover, the effect of new linen fabrics on apoptosis of THP-1 cells, as well as on the cell cycle of NHEK, HMCEV and THP-1, cells after 24 h of incubation was assessed. Cell viability tests were performed, and the proliferation potential of cells on Balb3T3 and NHEK cell lines was checked using the Sulforhodamine-B (SRB) test. Methods: The obtained fabrics from the traditional variety of flax (Nike), two transgenic types of flax (M50 and B14) and the combination of these two flax fibers (M50 + B14) were tested in direct contact in cell cultures. Background: Linen dressings were invented a few years ago but are still being worked on. ![]()
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